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Pathophysiology - what is the cause? Clinical significance - what does it mean? Diagnosis and treatment - what is the predictive value? These are questions that all clinicians should continue to ask themselves from the very beginning of medical training and throughout a lifetime of practice. Organised by body system, Mechanisms of Clinical Signs 3e describes the underlying pathway, differential diagnoses and value of the clinical signs seen during physical examination. Alphabetical listing of clinical signs Index by sign and conditions for easy reference Additional flow diagrams Clinical Pearls highlighting important clinical signs Summary of the evidence Access to chapter-based MCQs Access StudentConsult for: Clinical videos and audio of key signs Case-based MCQs An Enhanced eBook. The enhanced eBook allows the end user to access all of the text, figures, and references from the book on a variety of devices.